Matrix metalloproteinases and cardiovascular diseases
نویسندگان
چکیده
منابع مشابه
Matrix metalloproteinases and cardiovascular disease.
Matrix metalloproteinases (MMPs) are a group of endopeptidases with capacity to cleave components of extracellular matrix, such as collagen and elastin. The ability to modify the tissues is important for several aspects of normal and abnormal physiology. Approximately 20 different MMPs are identified, and they can be subdivided into different groups according to which components of the extracel...
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Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that have been increasingly linked to both normal physiology and abnormal pathology in the kidney. Collectively able to degrade all components of the extracellular matrix, MMPs were originally thought to antagonize the development of fibrotic diseases solely through digestion of excessive matrix. However, increasing ...
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Matrix metalloproteinases (MMPs) are a family of zinc dependent endopeptidases whose main function is to degrade and deposit structural proteins within the extracellular matrix (ECM). A dysregulation of MMPs is linked to vascular diseases. MMPs are classified into collagenases, gelatinases, membrane-type, metalloelastase, stromelysins, matrilysins, enamelysins, and unclassified subgroups. The p...
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ژورنال
عنوان ژورنال: "Arterial’naya Gipertenziya" ("Arterial Hypertension")
سال: 2009
ISSN: 2411-8524,1607-419X
DOI: 10.18705/1607-419x-2009-15-5-532-538